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Akio Nakane Selected Research

Transforming Growth Factor beta (TGF-beta)

9/2009Cyclosporine regulates intestinal epithelial apoptosis via TGF-beta-related signaling.
5/2009Inhibition of transforming growth factor-beta, hypoxia-inducible factor-1alpha and vascular endothelial growth factor reduced late rectal injury induced by irradiation.
8/2007Blockade of TGF-beta accelerates mucosal destruction through epithelial cell apoptosis.
2/2006The cytokine balance in the maintenance of a persistent infection with Salmonella enterica serovar Typhimurium in mice.
12/2004Transforming growth factor-{beta} regulates susceptibility of epithelial apoptosis in murine model of colitis.

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Akio Nakane Research Topics

Disease

31Infections
12/2021 - 01/2002
13Inflammation (Inflammations)
01/2024 - 01/2005
10Foodborne Diseases
07/2021 - 09/2007
10Staphylococcal Infections
10/2019 - 01/2005
10Septic Shock (Toxic Shock Syndrome)
10/2019 - 07/2005
9Vomiting
01/2019 - 09/2007
8Colitis
05/2023 - 12/2004
6Staphylococcal Food Poisoning
12/2020 - 02/2009
4Obesity
02/2022 - 01/2014
3Hypoxia (Hypoxemia)
01/2023 - 05/2008
3Bovine Mastitis
01/2019 - 05/2010
3Shock
09/2015 - 11/2012
3Bacterial Infections (Bacterial Infection)
09/2015 - 08/2006
3Neoplasms (Cancer)
02/2012 - 06/2007
3Ulcerative Colitis
09/2009 - 12/2004
2Cross Infection (Nosocomial Infection)
01/2023 - 11/2011
2Communicable Diseases (Infectious Diseases)
10/2019 - 06/2005
2Encephalomyelitis (Myeloencephalitis)
10/2018 - 01/2018
2Experimental Arthritis
01/2018 - 01/2014
2Hyperglycemia
11/2017 - 01/2005
2Fibrosis (Cirrhosis)
05/2009 - 05/2008
2Necrosis
01/2005 - 03/2002
2Hemolytic-Uremic Syndrome
07/2002 - 06/2002
1Alopecia (Baldness)
10/2023
1Immediate Hypersensitivity
12/2021
1Atopic Dermatitis (Atopic Eczema)
01/2020
1Mastitis
01/2019
1Bacteremia
11/2018
1Arthritis (Polyarthritis)
10/2018
1Wounds and Injuries (Trauma)
03/2018
1Skin Neoplasms (Skin Cancer)
01/2018
1Insulin Resistance
11/2017
1Reinfection
12/2016

Drug/Important Bio-Agent (IBA)

15Enterotoxins (Enterotoxin)IBA
07/2021 - 09/2007
13CytokinesIBA
12/2021 - 06/2002
9Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2011 - 03/2002
8Proteoglycans (Proteoglycan)IBA
12/2023 - 11/2010
8Interferon-gamma (Interferon, gamma)IBA
02/2011 - 01/2002
7Interleukin-10 (Interleukin 10)IBA
10/2019 - 01/2002
7muskIBA
01/2017 - 09/2007
6EmeticsIBA
01/2019 - 09/2007
5Interleukin-17 (Interleukin 17)IBA
12/2021 - 10/2010
5SuperantigensIBA
01/2020 - 11/2008
5VaccinesIBA
10/2019 - 09/2002
5staphylococcal enterotoxin CIBA
01/2019 - 01/2005
5Staphylococcal enterotoxin FIBA
01/2019 - 01/2013
5Messenger RNA (mRNA)IBA
06/2017 - 01/2005
5AntibodiesIBA
12/2016 - 09/2003
5Transforming Growth Factor beta (TGF-beta)IBA
09/2009 - 12/2004
4Proteins (Proteins, Gene)FDA Link
01/2024 - 07/2005
4Interleukin-6 (Interleukin 6)IBA
12/2021 - 11/2010
4Staphylococcal enterotoxin AIBA
01/2019 - 02/2009
3Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
01/2024 - 06/2005
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
10/2023 - 05/2008
3Dextran SulfateIBA
05/2023 - 08/2007
3LeptinIBA
02/2022 - 01/2005
3spleen fibrinolytic proteinase (human) (SFP)IBA
12/2020 - 07/2014
3Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
06/2015 - 01/2005
3Interleukin-12 (IL 12)IBA
11/2010 - 01/2002
3Macrophage Migration-Inhibitory FactorsIBA
09/2006 - 12/2004
3InterleukinsIBA
08/2006 - 01/2005
2Carrier Proteins (Binding Protein)IBA
01/2024 - 04/2013
2Virulence Factors (Pathogenicity Factors)IBA
01/2023 - 01/2019
2Fibronectins (Fibronectin)IBA
06/2017 - 04/2013
2bacterial fibronectin-binding proteinsIBA
06/2017 - 04/2013
2LipopolysaccharidesIBA
09/2015 - 03/2002
2Bacterial ToxinsIBA
09/2015 - 01/2014
2Peptides (Polypeptides)IBA
11/2012 - 11/2005
2InterferonsIBA
11/2012 - 08/2011
2Serotonin (5 Hydroxytryptamine)IBA
04/2012 - 09/2007
2Tretinoin (Retinoic Acid)FDA LinkGeneric
11/2010 - 01/2006
2Neutralizing AntibodiesIBA
05/2010 - 01/2005
2Glutathione Transferase (Glutathione S-Transferase)IBA
05/2010 - 07/2005
2Transforming Growth Factor beta1 (TGF beta 1)IBA
05/2009 - 05/2008
2GlucocorticoidsIBA
09/2006 - 12/2004
2Monoclonal AntibodiesIBA
04/2006 - 03/2002
2Interleukin-1 (Interleukin 1)IBA
06/2005 - 01/2005
1Membrane Glycoproteins (Membrane Glycoprotein)IBA
01/2024
1aconitate decarboxylaseIBA
01/2024
1Macrophage Colony-Stimulating FactorIBA
01/2024
1Insulin (Novolin)FDA Link
12/2023
1Endothelial Growth FactorsIBA
12/2023
1IGF Type 1 Receptor (IGF 1 Receptor)IBA
10/2023
1Vitamin A (Retinol)FDA LinkGeneric
05/2023
1InflammasomesIBA
05/2023
1Sterol Regulatory Element Binding Protein 1IBA
02/2022
1Toll-Like Receptors (Toll-Like Receptor)IBA
12/2021
1Immunologic Adjuvants (Immunologic Adjuvant)IBA
12/2021
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2020
1Histamine (Histamine Dihydrochloride)FDA Link
01/2019
1Pyrimidine DimersIBA
01/2018
1Glucose (Dextrose)FDA LinkGeneric
11/2017
1AntigensIBA
06/2017
1Peroxidase (Myeloperoxidase)IBA
06/2017
1Listeria monocytogenes hlyA protein (listeriolysin O)IBA
12/2016
1ChemokinesIBA
06/2015
1CoagulaseIBA
07/2014

Therapy/Procedure

3Oral Administration
10/2018 - 11/2010
2Therapeutics
01/2012 - 11/2011
2Radiotherapy
05/2009 - 06/2007